In the Mera Park region of Nepal, a South African member developed worsening symptoms of altitude sickness that progressed to high-altitude cerebral edema (HACE). Despite initial treatment, his condition required urgent helicopter evacuation to a hospital. After further treatment, he was diagnosed with high-altitude pulmonary edema (HAPE), HACE and several related complications. He was discharged in improved condition and the case was reviewed with no concerns noted about the medical care provided.